So after thinking about this the best way to do it is to make arbitrary URL's able to effect children by using a loop that traverses through the accessed URL to match it to an entry in the database. So for example the URL http://www.wpmason.com/our-plugins/custom-search-forms/documentation/customization/ will do the matching as follows.

http://www.wpmason.com/our-plugins/custom-search-forms/documentation/

http://www.wpmason.com/our-plugins/custom-search-forms/

http://www.wpmason.com/our-plugins/

It will stop on the first match it makes and use that to disable plugins. There is now a checkbox under the URL entry box in the admin to have the url effect children. If the accessed URL exactly matches a URL that has been entered or if it is a post/page/custom post_type that has plugins disabled on its admin page then this matching will be skipped. So in other words the post/page/custom post_type admin page takes precedence over this fuzzy matching.

This approach is quick and it shouldn't slow your site down trying to make a match. With the way that the plugin is built and the fact that it works outside of wordpress this is the closest I can come to regular expression matching. I'm testing the new version now to make sure everything is still working and I can hopefully release it tomorrow or Monday. I will let you know when you can download it.

I also want to add the ability to ignore the protocol when doing matching because https is causing me some issues on a couple of sites. This is going to be a little tricky since all the URL's you have in your database will have to be redone if I simply ignore it and plus some people might not want to ignore it. So I'm going to make it optional by checking a checkbox on the admin page. This is going to be the next release and I can hopefully get that done by the end of next week.

sound great I took a fast look and will give you news later
thank you for your work

Yes that is how it works. Make sure you have Fuzzy URL Matching enabled on the main settings page under Plugin Organizer in the WP admin menu and that you have the checkbox "Also effect children" checked for the URL. It will stop searching for a match at the first URL found. So if you enter http://www.main-website.com/wordpress-blog/page/ and http://www.main-website.com/wordpress-blog/. It will stop looking when it finds http://www.main-website.com/wordpress-blog/page/ because that will be the first match.

Thanks, Jeff, perfect !

Now my URL Admin list is way leaner and meaner. Sometimes, Global just doesn't work for certain applications, so this latest update is great, thumbs all the way up !